Biohacking: Somewhere between zero and epsilon Peter Attia has something to say to all these alternative medicine biohackers out there. 1. “There are few concepts in the longevity space that inspire my disdain more than the b-word: biohacking – the notion that individuals can enhance health, performance, and lifespan by adopting an array of experimental, [...]

The Doctor AI debate It’s still very early in the era of A.I. in medicine, especially with LLMs. Progress in medical A.I. won’t occur in a straight line. Doctor Eric Topol does a very good job summarizing some of the latest findings. One big step forward with a 16.000 patient study that showed a statistically [...]

Extend your lifespan by 12 years. Get the fundamentals right The data says that if you get these 5 things right at the age of 50 you will extend your lifespan by 12 (male) to 14 (female) years. Don't smoke Stay active Normal weight Modest Alcohol Good Diet Add annual “early detection” health check-ups to [...]

Excellent Bloomberg interview with legendary hedge fund icon Edward Thorp (age 91) on longevity and managing risk. Some quotes: 1. You can minimize that risk by what you eat and the kind of exercise you do and by regular checkups, so that if something is going wrong, you can address it before it gets worse. [...]

1. If your primary goal is general wellness and longevity, a new study found that total aerobic activity predicts all-cause mortality and cardiovascular disease better than intensity. 2. The scientists analyzed the data of nearly 40,000 participants over a 12-year period. While there are benefits to training with intensity, getting enough movement is what matters [...]

Dr. Benjamin Levine is a legend in the field of exercise physiology. He ran a study that shows that: 1. as we age, the heart tends to get smaller and stiffer. This impacts its efficiency, reducing exercise capacity and potentially elevating heart failure risk 2. But remarkably, 2 years of vigorous exercise in sedentary 50-year-olds [...]

Peter Attia on the huge importance of strength training for longevity purposes. "Exercise, and in particular resistance training, is one of the most effective ways to combat sarcopenia, and the so-called “age-related” declines in muscle composition are not as unavoidable as many might assume. The results of this study demonstrate that heavy resistance training creates [...]

Bigger than AI: 'We're at the beginning of the second longevity revolution' The concept of an aging population is often seen as a societal burden, but London Business School professor of economics, Andrew J Scott, challenges this perception in his new book, The Longevity Imperative. Scott introduces the evergreen agenda, advocating for a sustainable lifestyle [...]

1. Start early taking care of your heart Most people think of heart disease as a problem for older people. While it is true that the older you are, the higher the risk of a heart attack, the process of plaque buildup starts early in life. How early? Over half of all ‘healthy’ heart arteries [...]

Lifetime Risk Of A Heart Attack - An Example Take a 45-year-old female with high LDL cholesterol (155 mg/dl), overweight and with high blood pressure (134 mmHg) and has a family history of heart disease. Not extreme values and not an unusual patient. That person’s lifetime risk of a heart attack is 32%. But now [...]